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Interest income Investment Income, Interest Cash and cash equivalents Cash and Cash Equivalents, Fair Value Disclosure Schedule of Financial Assets Measured at Fair Value on a Recurring Basis Fair Value, Assets Measured on Recurring Basis [Table Text Block] Operating Lease, Liability, Total Present value of lease liabilities Operating Lease, Liability Debt Securities, Available-for-Sale [Table Text Block] Summary of Amortized Cost, Unrealized Gain (Loss) Recognized in AOCI and Fair Value of Available-for-Sale Securities Interest received Interest Received Interest received. Measurement Frequency Measurement Frequency [Axis] Commitments and contingencies (note 10) Commitments and Contingencies Incremental stock-based compensation expense Share-Based Payment Arrangement, Plan Modification, Incremental Cost Research and development services Research And Development Services Research and development services. Weighted Average Number of Shares Outstanding, Diluted, Total Diluted Weighted Average Number of Shares Outstanding, Diluted Significant Accounting Policies [Text Block] Significant Accounting Policies Accounts Receivable, after Allowance for Credit Loss, Current, Total Accounts receivable Accounts Receivable, after Allowance for Credit Loss, Current Research and Development Arrangement, Contract to Perform for Others, Type Research and Development Arrangement, Contract to Perform for Others, Type [Axis] Exercise of pre-funded warrants Exercised Number Of Warrants Exercised Number of warrants exercised. Lessee, Operating Lease, Renewal Term Operating lease extension term Total future minimum lease payments Lessee, Operating Lease, Liability, to be Paid Exchange Agreement [Member] Exchange Agreement [Member] Exchange agreement. Entity Small Business Entity Small Business Sales Based Milestone [Member] Sales Based Milestone [Member] Sales-based milestone. U.S. Treasuries [Member] US Treasuries [Member] US Treasury Securities [Member] Foreign exchange gain Foreign Currency Transaction Gain (Loss), before Tax, Total Gain (Loss), Foreign Currency Transaction, before Tax Foreign exchange gain Commitments And Contingencies [Table] Commitments And Contingencies [Table] Commitments and contingencies. Stock issued during period value conversion of pre funded warrant to common shares. Stock Issued During Period Value Conversion Of Pre Funded Warrant To Common Shares Conversion of pre-funded warrants to common shares (note 9b) Number of operating leases Lessee Number Of Operating Leases Lessee, number of operating leases. Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Weighted Average Exercise Price Outstanding, Beginning of period Weighted Average Exercise Price Outstanding, End of period Weighted Average Number of Shares Outstanding Reconciliation [Abstract] Weighted-average common shares outstanding (note 4): Asset Class Asset Class [Axis] Measurement Frequency Measurement Frequency [Domain] Level 3 [Member] Fair Value, Inputs, Level 3 [Member] Weighted average remaining lease term (years) Operating Lease, Weighted Average Remaining Lease Term Unrealized loss on available-for-sale securities (note 6) OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax, Total Fair value of stock options exercised on a cashless basis Fair Value Of Stock Options Exercised On Cashless Basis The aggregate grant-date fair value of stock options exercised via net exercise (cashless) during the reporting period as calculated by applying the disclosed option pricing methodology. Commitments And Contingencies [Line Items] Commitments And Contingencies [Line Items] Commitments and contingencies. Total Accounts Payable and Accrued Liabilities, Current Accounts payable and accrued expenses (note 8) October 2021 Pre Funds Warrants Outstanding Date Issuance October Two Thousand Twenty One [Member] Pre funds warrants outstanding date issuance october two thousand twenty one.